1141855-86-8
1141855-86-8
Chemical Structure
WYE-151650
- CAS No.: 1141855-86-8
- Formula:C24H19N7O2
- Molecular Weight:437.45
IUPAC Name: 1-(9-((1R,4R)-4-hydroxy-1,2,3,4-tetrahydronaphthalen-1-yl)-7-methyl-8-oxo-8,9-dihydro-7H-purin-2-yl)-1H-benzo[d]imidazole-6-carbonitrile
InChIKey: SYQKUEMEGFISAD-WIYYLYMNSA-N
SMILES: N#CC1=CC=C2N=CN(C3=NC=C4N(C)C(N([C@@H]5CC[C@@H](O)C6=C5C=CC=C6)C4=N3)=O)C2=C1
Biological Activity: WYE-151650 is a selective JAK-3 inhibitor. WYE-151650 suppresses IL-2-induced STAT-5 phosphorylation and cell proliferation mediated by JAK-3. WYE-151650 is promising for research of autoimmune diseases[1].
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WYE-151650 | WYE-151650 is a selective JAK-3 inhibitor. WYE-151650 suppresses IL-2-induced STAT-5 phosphorylation and cell proliferation mediated by JAK-3. WYE-151650 is promising for research of autoimmune diseases. | |||||||||||||||||||||
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References
Keywords
