2. Epigenetics Stem Cell/Wnt Protein Tyrosine Kinase/RTK JAK/STAT Signaling
  3. JAK STAT
  4. WYE-151650

WYE-151650 is a selective JAK-3 inhibitor. WYE-151650 suppresses IL-2-induced STAT-5 phosphorylation and cell proliferation mediated by JAK-3. WYE-151650 is promising for research of autoimmune diseases.

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WYE-151650

WYE-151650 Estructura química

No. CAS : 1141855-86-8

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WYE-151650 Related Antibodies

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STAT3 STAT5 STAT6 STAT1

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Descripciòn

WYE-151650 is a selective JAK-3 inhibitor. WYE-151650 suppresses IL-2-induced STAT-5 phosphorylation and cell proliferation mediated by JAK-3. WYE-151650 is promising for research of autoimmune diseases[1].

IC50 & Target

JAK3

 

STAT5

 

Peso molecular

437.45

Fòrmula

C24H19N7O2
No. CAS
SMILES

N#CC1=CC=C2N=CN(C3=NC=C4N(C)C(N([C@@H]5CC[C@@H](O)C6=C5C=CC=C6)C4=N3)=O)C2=C1
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Room temperature in continental US; may vary elsewhere.
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WYE-151650 Related Classifications

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  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

WYE-1516501141855-86-8WYE151650WYE 151650JAKSTATJanus kinaseJAK-3STAT-5 phosphorylationautoimmune diseasesInhibitorinhibitorinhibit

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Nombre del producto:
WYE-151650
Cat. No.:
HY-120457
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