1142407-60-0
Chemical Structure
DHFR-IN-5 hydrochloride
- CAS No.: 1142407-60-0
- Formula:C18H25ClN4O4
- Molecular Weight:396.87
InChIKey: BVRPZXMKYBDROK-UHFFFAOYSA-N
SMILES: O=C(CCC1=C(OCCCOC2=C(CC)N=C(N)N=C2N)C=CC=C1)O.Cl
Biological Activity: DHFR-IN-5 hydrochloride is a potent and orally active dihydrofolate reductase (DHFR) inhibitor with a Ki value of 0.54 nM for quadruple mutant Plasmodium falciparum DHFR. DHFR-IN-5 hydrochloride shows anti-malaria activity[1].
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DHFR-IN-5 hydrochloride | DHFR-IN-5 hydrochloride is a potent and orally active dihydrofolate reductase (DHFR) inhibitor with a Ki value of 0.54 nM for quadruple mutant Plasmodium falciparum DHFR. DHFR-IN-5 hydrochloride shows anti-malaria activity. | |||||||||||||||||||||
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Keywords