1142407-81-5
1142407-81-5
Chemical Structure
DHFR-IN-5
- CAS No.: 1142407-81-5
- Formula:C18H24N4O4
- Molecular Weight:360.41
IUPAC Name: 3-(2-(3-((2,4-diamino-6-ethylpyrimidin-5-yl)oxy)propoxy)phenyl)propanoic acid
InChIKey: VDGXZSSDCDPCRF-UHFFFAOYSA-N
SMILES: O=C(CCC1=C(OCCCOC2=C(CC)N=C(N)N=C2N)C=CC=C1)O
Biological Activity: DHFR-IN-5 is a potent and orally active dihydrofolate reductase (DHFR) inhibitor with a Ki value of 0.54 nM for quadruple mutant Plasmodium falciparum DHFR. DHFR-IN-5 shows anti-malaria activity[1].
| Cat. No. | Product Name | Purity | Description | Pricing | |||||||||||||||||||
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DHFR-IN-5 | 99.27% | DHFR-IN-5 is a potent and orally active dihydrofolate reductase (DHFR) inhibitor with a Ki value of 0.54 nM for quadruple mutant Plasmodium falciparum DHFR. DHFR-IN-5 shows anti-malaria activity. | ||||||||||||||||||||
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References
Keywords
