1173022-56-4
1173022-56-4
Chemical Structure
4-Hydroxymephenytoin-d3
- CAS No.: 1173022-56-4
- Formula:C12H11D3N2O3
- Molecular Weight:237.27
IUPAC Name: 5-ethyl-5-(4-hydroxyphenyl)-3-(methyl-d3)imidazolidine-2,4-dione
InChIKey: OQPLORUDZLXXPD-BMSJAHLVSA-N
SMILES: CCC1(C2=CC=C(C=C2)O)C(N(C(N1)=O)C([2H])([2H])[2H])=O
Biological Activity: 4-Hydroxymephenytoin-d3 is the deuterium labeled 4-Hydroxymephenytoin. 4-Hydroxymephenytoin is a metabolism of an antiepileptic agent mephenytoin, which is used as a CYP2C19 substrate[1][2].
| Cat. No. | Product Name | Purity | Description | Pricing | |||||||||||||||||||
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4-Hydroxymephenytoin-d3 | 99.05% | 4-Hydroxymephenytoin-d3 is the deuterium labeled 4-Hydroxymephenytoin. 4-Hydroxymephenytoin is a metabolism of an antiepileptic agent mephenytoin, which is used as a CYP2C19 substrate. | ||||||||||||||||||||
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4-Hydroxymephenytoin (Standard) | ≥98% | 4-Hydroxymephenytoin (Standard) is the analytical standard of 4-Hydroxymephenytoin. This product is intended for research and analytical applications. 4-Hydroxymephenytoin is a metabolism of an antiepileptic agent mephenytoin, which is used as a CYP2C19 substrate. | ||||||||||||||||||||
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4-Hydroxymephenytoin | 99.77% | 4-Hydroxymephenytoin is a metabolism of an antiepileptic agent mephenytoin, which is used as a CYP2C19 substrate. | ||||||||||||||||||||
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References
- [1]. Russak EM, et al. Impact of Deuterium Substitution on the Pharmacokinetics of Pharmaceuticals. Ann Pharmacother. 2019;53(2):211-216. [Content Brief]
- [2]. Tanaka M, et al. Simple and selective assay of 4-hydroxymephenytoin in human urine using solid-phase extraction and high-performance liquid chromatography with electrochemical detection and its preliminary application to phenotyping test. J Chromatogr B Biomed Appl. 1996 Feb 9;676(1):87-94. [Content Brief]
