1187917-12-9
Chemical Structure
AIC-292
- CAS No.: 1187917-12-9
- Formula:C19H12Cl2F2N4O2
- Molecular Weight:437.23
IUPAC Name: 1-(1-(3-chloro-4-fluorophenyl)-5-(3-chloro-5-fluorophenyl)-1H-pyrazole-3-carbonyl)imidazolidin-4-one
InChIKey: JPOJKNJIKXMZRB-UHFFFAOYSA-N
SMILES: O=C1NCN(C(C2=NN(C3=CC=C(F)C(Cl)=C3)C(C4=CC(F)=CC(Cl)=C4)=C2)=O)C1
Biological Activity: AIC-292 is a potent and selective inhibitor of HIV-1 nonnucleoside reverse transcriptase. AIC-292 inhibits wild-type HIV-1 laboratory strains at low nanomolar concentrations. AIC-292 displays potent antiviral in vivo efficacy in a mouse xenograft model. AIC-292 has the potential for the research of HIV-1 infection[1].
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AIC-292 | AIC-292 is a potent and selective inhibitor of HIV-1 nonnucleoside reverse transcriptase. AIC-292 inhibits wild-type HIV-1 laboratory strains at low nanomolar concentrations. AIC-292 displays potent antiviral in vivo efficacy in a mouse xenograft model. AIC-292 has the potential for the research of HIV-1 infection. | |||||||||||||||||||||
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Keywords
