1190221-46-5
1190221-46-5
Chemical Structure
PAI-1-IN-2
- CAS No.: 1190221-46-5
- Formula:C21H17ClN2O6
- Molecular Weight:428.83
IUPAC Name: 5-chloro-2-(2-(2-((3-(furan-2-yl)phenyl)amino)-2-oxoethoxy)acetamido)benzoic acid
InChIKey: OLNFSGSWFUVNFF-UHFFFAOYSA-N
SMILES: O=C(O)C1=CC(Cl)=CC=C1NC(=O)COCC(=O)NC2=CC=CC(=C2)C=3OC=CC3
Biological Activity: PAI-1-IN-2 is a PAI-1 inhibitor with an IC50 of 7.45 μM. By inhibiting PAI-1, PAI-1-IN-2 relieves the inhibitory effect of PAI-1 on tPA and uPA, thereby increasing plasmin levels and promoting fibrinolysis. PAI-1-IN-2 can be used in research related to cardiovascular diseases and cancers[1].
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PAI-1-IN-2 | PAI-1-IN-2 is a PAI-1 inhibitor with an IC50 of 7.45 μM. By inhibiting PAI-1, PAI-1-IN-2 relieves the inhibitory effect of PAI-1 on tPA and uPA, thereby increasing plasmin levels and promoting fibrinolysis. PAI-1-IN-2 can be used in research related to cardiovascular diseases and cancers. | |||||||||||||||||||||
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References
Keywords
