119139-23-0
119139-23-0
Chemical Structure
Bisindolylmaleimide IV
Synonym(s): Arcyriarubin A
- CAS No.: 119139-23-0
- Formula:C20H13N3O2
- Molecular Weight:327.34
IUPAC Name: 3,4-di(1H-indol-3-yl)-1H-pyrrole-2,5-dione
InChIKey: DQYBRTASHMYDJG-UHFFFAOYSA-N
SMILES: O=C(C(C1=CNC2=C1C=CC=C2)=C3C4=CNC5=C4C=CC=C5)NC3=O
Biological Activity: Bisindolylmaleimide IV (Arcyriarubin A) is a potent protein kinase C (PKC) inhibitor, with IC50s ranging from 0.1 to 0.55 μM. Bisindolylmaleimide IV also inhibits PKA (IC50=3.1-11.8μM)[1]. Bisindolylmaleimide IV is a potent, selective inhibitor of human cytomegalovirus (HCMV) replication in cell culture with an IC50 of 0.2 μM[2].
| Cat. No. | Product Name | Purity | Description | Pricing | |||||||||||||||||||
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Bisindolylmaleimide IV | 99.71% | Bisindolylmaleimide IV (Arcyriarubin A) is a potent protein kinase C (PKC) inhibitor, with IC50s ranging from 0.1 to 0.55 μM. Bisindolylmaleimide IV also inhibits PKA (IC50=3.1-11.8μM). Bisindolylmaleimide IV is a potent, selective inhibitor of human cytomegalovirus (HCMV) replication in cell culture with an IC50 of 0.2 μM. | ||||||||||||||||||||
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Bisindolylmaleimide IV (Standard) | ≥98% | Bisindolylmaleimide IV (Standard) is the analytical standard of Bisindolylmaleimide IV. This product is intended for research and analytical applications. Bisindolylmaleimide IV (Arcyriarubin A) is a potent protein kinase C (PKC) inhibitor, with IC50s ranging from 0.1 to 0.55 μM. Bisindolylmaleimide IV also inhibits PKA (IC50=3.1-11.8μM). Bisindolylmaleimide IV is a potent, selective inhibitor of human cytomegalovirus (HCMV) replication in cell culture with an IC50 of 0.2 μM. | ||||||||||||||||||||
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References
