1194954-52-3
Chemical Structure
(rel)-PRT062607
Synonym(s): (rel)-P505-15;(rel)-PRT-2607;(rel)-BIIB-057
- CAS No.: 1194954-52-3
- Formula:C19H23N9O
- Molecular Weight:393.45
IUPAC Name: 4-((3-(2H-1,2,3-triazol-2-yl)phenyl)amino)-2-(((1R,2S)-2-aminocyclohexyl)amino)pyrimidine-5-carboxamide
InChIKey: TXGKRVFSSHPBAJ-JKSUJKDBSA-N
SMILES: NC(C(C(NC1=CC(N2N=CC=N2)=CC=C1)=N3)=CN=C3N[C@H]4[C@H](CCCC4)N)=O
Biological Activity: (rel)-PRT062607 ((rel)-P505-15) is the relative configuration of PRT062607 (HY-15322). PRT062607 is a highly selective inhibitor of Syk kinase, with an IC50 value of 1-2 nM, and is more than 80 times less potent against Fgr, Lyn, FAK, Pyk2, and Zap70.
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(rel)-PRT062607 | (rel)-PRT062607 ((rel)-P505-15) is the relative configuration of PRT062607 (HY-15322). PRT062607 is a highly selective inhibitor of Syk kinase, with an IC50 value of 1-2 nM, and is more than 80 times less potent against Fgr, Lyn, FAK, Pyk2, and Zap70. | |||||||||||||||||||||
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Keywords
