119539-81-0
Chemical Structure
Withacoagin
Synonym(s): (+)-Withacoagin
- CAS No.: 119539-81-0
- Formula:C28H38O5
- Molecular Weight:454.60
InChIKey: UYRXFMXVVKNLDH-VHXUWDKCSA-N
SMILES: C[C@@]12[C@]3([H])[C@](C=C[C@]1(CC=CC2=O)O)([H])[C@@]4([H])[C@](CC3)([C@@](CC4)([H])[C@@](O)([C@@]5([H])CC(C)=C(C(O5)=O)C)C)C
Biological Activity: Withacoagin is a withanolide that can be isolated from the roots of Withania coagulans. Withacoagin has various biological activites such as adaptogenic, anti-inflammatory, and antioxidant properties. Withacoagin regulates the activity of various enzymes and pathways related to oxidative stress and inflammation. Withacoagin can attenuates HIV-1 infection[1][2].
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Withacoagin | Withacoagin is a withanolide that can be isolated from the roots of Withania coagulans. Withacoagin has various biological activites such as adaptogenic, anti-inflammatory, and antioxidant properties. Withacoagin regulates the activity of various enzymes and pathways related to oxidative stress and inflammation. Withacoagin can attenuates HIV-1 infection. | |||||||||||||||||||||
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- [1]. Partha Neogi, et al., Withacoagin, a New Withanolide from Withania coagulans Roots, Bulletin of the Chemical Society of Japan, Volume 61, Issue 12, 1988.
- [2]. Jadaun P, et al., Withania somnifera extracts induced attenuation of HIV-1: a mechanistic approach to restrict viral infection. Virol J. 2023 Aug 3;20(1):173. [Content Brief]
Keywords
