1197522-21-6

KIF18A-IN-4 Chemical Structure
1197522-21-6

Chemical Structure

KIF18A-IN-4

  • CAS No.: 1197522-21-6
  • Formula:C22H27N3O3S
  • Molecular Weight:413.53

IUPAC Name: N-(3-(cyclopentylsulfonyl)phenyl)-2-(piperidin-1-yl)nicotinamide

InChIKey: PGNDBHSSJBNDJL-UHFFFAOYSA-N

SMILES: O=S(C1=CC=CC(NC(C2=C(N3CCCCC3)N=CC=C2)=O)=C1)(C4CCCC4)=O

Biological Activity: KIF18A-IN-4 is a moderately potent ATP and microtubule (MT) noncompetitive KIF18A inhibitor (IC50=6.16 μM). KIF18A-IN-4 has selectivity against a large panel of mitotic kinesins and kinases, and does not show any direct effects on tubulin assembly. KIF18A-IN-4 exhibits anti-tumor activity[1].

Cat. No. Product Name Purity Description Pricing
HY-145827 		KIF18A-IN-4 KIF18A-IN-4 is a moderately potent ATP and microtubule (MT) noncompetitive KIF18A inhibitor (IC50=6.16 μM). KIF18A-IN-4 has selectivity against a large panel of mitotic kinesins and kinases, and does not show any direct effects on tubulin assembly. KIF18A-IN-4 exhibits anti-tumor activity.
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