120013-56-1
120013-56-1
Chemical Structure
6-O-Desmethyl donepezil
- CAS No.: 120013-56-1
- Formula:C23H27NO3
- Molecular Weight:365.47
IUPAC Name: 2-((1-benzylpiperidin-4-yl)methyl)-6-hydroxy-5-methoxy-2,3-dihydro-1H-inden-1-one
InChIKey: DJRBBQJREIMIEU-UHFFFAOYSA-N
SMILES: O=C1C(CC2CCN(CC3=CC=CC=C3)CC2)CC4=C1C=C(O)C(OC)=C4
Biological Activity: 6-O-Desmethyl donepezil is the metabolite of Donepezil (HY-14566). 6-O-Desmethyl donepezil is an inhibitor for hERG channel with an IC50 of 1 μM[1].
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6-O-Desmethyl donepezil | 6-O-Desmethyl donepezil is the metabolite of Donepezil (HY-14566). 6-O-Desmethyl donepezil is an inhibitor for hERG channel with an IC50 of 1 μM. | |||||||||||||||||||||
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6-O-Desmethyl donepezil-d5 | 6-O-Desmethyl donepezil-d5 is the deuterium labeled 6-O-Desmethyl donepezil. | |||||||||||||||||||||
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6-O-Desmethyl donepezil-d5 hydrochloride | 6-O-Desmethyl donepezil-d5 (hydrochloride) is deuterium labeled 6-O-Desmethyl donepezil. | |||||||||||||||||||||
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6-O-Desmethyl donepezil-d7 | 6-O-Desmethyl donepezil-d7 is deuterated labeled 6-O-Desmethyl donepezil. | |||||||||||||||||||||
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References
