1202891-16-4
1202891-16-4
Chemical Structure
ARRY-502
- CAS No.: 1202891-16-4
- Formula:C26H23Cl2NO6
- Molecular Weight:516.37
IUPAC Name: (S)-6-chloro-7-(4-((4-chloro-2-methoxyphenethyl)carbamoyl)phenoxy)chromane-4-carboxylic acid
InChIKey: QIDYUNXQPQEJEC-IBGZPJMESA-N
SMILES: OC([C@@H]1C2=CC(Cl)=C(OC3=CC=C(C=C3)C(NCCC4=C(C=C(C=C4)Cl)OC)=O)C=C2OCC1)=O
Biological Activity: ARRY-502 is an orally active, potent and selective CRTh2 antagonist. ARRY-502 blocks PGD2-mediated Th2 inflammation (e.g., eosinophil activation, airway hyperresponsiveness). ARRY-502 is promising for research of Th2-related asthma[1].
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ARRY-502 | ARRY-502 is an orally active, potent and selective CRTh2 antagonist. ARRY-502 blocks PGD2-mediated Th2 inflammation (e.g., eosinophil activation, airway hyperresponsiveness). ARRY-502 is promising for research of Th2-related asthma. | |||||||||||||||||||||
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References
Keywords
