1216997-87-3
Chemical Structure
2-Amino-3,4,8-trimethylimidazo[4,5-f]quinoxaline-d3
- CAS No.: 1216997-87-3
- Formula:C12H10D3N5
- Molecular Weight:230.28
IUPAC Name: 4,8-dimethyl-3-(methyl-d3)-3H-imidazo[4,5-f]quinoxalin-2-amine
InChIKey: LAZSIJHHPMHKQI-HPRDVNIFSA-N
SMILES: CC1=CN=C(C2=N1)C=C(C3=C2N=C(N3C([2H])([2H])[2H])N)C
Biological Activity: 2-Amino-3,4,8-trimethylimidazo[4,5-f]quinoxaline-d3 is the deuterium labeled 2-Amino-3,4,8-trimethylimidazo[4,5-f]quinoxaline.
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2-Amino-3,4,8-trimethylimidazo[4,5-f]quinoxaline-d3 | 2-Amino-3,4,8-trimethylimidazo[4,5-f]quinoxaline-d3 is the deuterium labeled 2-Amino-3,4,8-trimethylimidazo[4,5-f]quinoxaline. | |||||||||||||||||||||
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4,8-DiMeIQx | 4,8-DiMeIQx is an orally active mutagen, selective dopaminergic neurotoxicant, and DNA damaging agent. 4,8-DiMeIQx can be isolated from cooked beef, sausage, pork, and chicken. 4,8-DiMeIQx induces reverse mutations in *Salmonella typhimurium* TA98 in the presence or absence of S9 mix, and forms DNA adducts in vivo in rat liver. 4,8-DiMeIQx exhibits selective neurotoxicity toward dopaminergic neurons. 4,8-DiMeIQx shows no activity against non-dopaminergic neurons. 4,8-DiMeIQx can be used in studies related to Parkinson's disease and colorectal cancer. | |||||||||||||||||||||
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