1228150-86-4
Chemical Structure
Topoisomerase I inhibitor 9
- CAS. Nr.: 1228150-86-4
- Formula:C23H15Br2FN2
- Molecular Weight:498.19
InChIKey: QHISLSGSRBIKOS-UHFFFAOYSA-N
SMILES: FC1=CC=C(C(C2=CNC3=C2C=C(Br)C=C3)C4=CNC5=C4C=C(Br)C=C5)C=C1
Biological Activity: Topoisomerase I inhibitor 9 (compound 3d) is a leishmanial topoisomerase IB inhibitor. Topoisomerase I inhibitor 9 has antileishmanial activity against L. donovani promastigotes, with the IC50 of 34.81μM[1].
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Topoisomerase I inhibitor 9 | Topoisomerase I inhibitor 9 (compound 3d) is a leishmanial topoisomerase IB inhibitor. Topoisomerase I inhibitor 9 has antileishmanial activity against L. donovani promastigotes, with the IC50 of 34.81μM. | |||||||||||||||||||||
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Keywords