1236141-96-0
1236141-96-0
Chemical Structure
Microtubule inhibitor 3
- CAS No.: 1236141-96-0
- Formula:C26H23FN4O3
- Molecular Weight:458.48
IUPAC Name: (Z)-3-((5-(tert-butyl)-1H-imidazol-4-yl)methylene)-6-((Z)-3-(4-fluorobenzoyl)benzylidene)piperazine-2,5-dione
InChIKey: PPBYGOIXJTYVGU-FDYZEBBJSA-N
SMILES: CC(C)(C1=C(N=CN1)/C=C2NC(/C(NC\2=O)=C/C3=CC(C(C4=CC=C(C=C4)F)=O)=CC=C3)=O)C
Biological Activity: Compounds 17O (ic50= 14.0 nm, NCI-H460) and 17p (ic50= 2.9 nm, NCI-H460) and furan groups showed effective cytotoxic activity against various human cancer cell lines at the nanomolar level.
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Microtubule inhibitor 3 | Compounds 17O (ic50= 14.0 nm, NCI-H460) and 17p (ic50= 2.9 nm, NCI-H460) and furan groups showed effective cytotoxic activity against various human cancer cell lines at the nanomolar level. | |||||||||||||||||||||
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Keywords
