124027-47-0
124027-47-0
Chemical Structure
Velnacrine
Synonym(s): HP 029 free base; Hydroxytacrine
- CAS. Nr.: 124027-47-0
- Formula:C13H14N2O
- Molecular Weight:214.26
IUPAC Name: 9-amino-1,2,3,4-tetrahydroacridin-1-ol
InChIKey: HLVVITIHAZBPKB-UHFFFAOYSA-N
SMILES: OC1CCCC2=NC3=CC=CC=C3C(N)=C21
Biological Activity: Velnacrine (HP 029 free base) is an inhibitor for acetylcholinesterase (AChE), with an IC50 of 3.27 μM. Velnacrine reverses the Scopolamine (HY-N0296)-induced amnesia in rat models, and exhibits acute toxicity with LD50 of 65 mg/kg[1].
| Art. -Nr. | Produktname | Reinheit | Beschreibung | Pricing | |||||||||||||||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
|
|
Velnacrine | 98.79% | Velnacrine (HP 029 free base) is an inhibitor for acetylcholinesterase (AChE), with an IC50 of 3.27 μM. Velnacrine reverses the Scopolamine (HY-N0296)-induced amnesia in rat models, and exhibits acute toxicity with LD50 of 65 mg/kg. | ||||||||||||||||||||
|
loading...
/
|
|||||||||||||||||||||||
|
|
Velnacrine-d4 hydrochloride | 98.60% | Velnacrine-d4 (hydrochloride) is deuterium labeled Velnacrine. | ||||||||||||||||||||
|
loading...
/
|
|||||||||||||||||||||||
|
|
Velnacrine-d4 | Velnacrine-d4 is deuterium labeled Velnacrine. | |||||||||||||||||||||
|
loading...
/
|
|||||||||||||||||||||||
|
|
Velnacrine-d3 maleate | Velnacrine-d3 (maleate) is the deuterium labeled Velnacrine maleate. | |||||||||||||||||||||
|
loading...
/
|
|||||||||||||||||||||||
References
