1246820-20-1
1246820-20-1
Chemical Structure
Medetomidine-d3 hydrochloride
Synonym(s): MPV785-d3
- CAS No.: 1246820-20-1
- Formula:C13H14D3ClN2
- Molecular Weight:239.76
IUPAC Name: 5-(1-(2,3-dimethylphenyl)ethyl-2,2,2-d3)-1H-imidazole hydrochloride
InChIKey: VPNGEIHDPSLNMU-FJCVKDQNSA-N
SMILES: CC1=C(C)C(C(C2=CN=CN2)C([2H])([2H])[2H])=CC=C1.Cl
Biological Activity: Medetomidine-d3 (hydrochloride) is the deuterium labeled Medetomidine hydrochloride. Medetomidine hydrochloride is an agonist of adrenergic alpha-2 receptor[1][2].
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Medetomidine-d3 hydrochloride | Medetomidine-d3 (hydrochloride) is the deuterium labeled Medetomidine hydrochloride. Medetomidine hydrochloride is an agonist of adrenergic alpha-2 receptor. | |||||||||||||||||||||
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Medetomidine hydrochloride (Standard) | ≥98% | Medetomidine (hydrochloride) (Standard) is the analytical standard of Medetomidine (hydrochloride). This product is intended for research and analytical applications. Medetomidine hydrochloride is an orally active α2-adrenoceptor agonist (Ki: 1.08 nM). Medetomidine hydrochloride has sedative and analgesic effects. Medetomidine hydrochloride can cause peripheral vasoconstriction through the activation of α2 adrenoceptors on blood vessels. | ||||||||||||||||||||
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Medetomidine-13C,d3 hydrochloride | 99.48% | Medetomidine-13C,d3 (hydrochloride) is a deuterated labeled Medetomidine (hydrochloride). Medetomidine hydrochloride is an orally active α2-adrenoceptor agonist (Ki: 1.08 nM). Medetomidine hydrochloride has sedative and analgesic effects. Medetomidine hydrochloride can cause peripheral vasoconstriction through the activation of α2 adrenoceptors on blood vessels. | ||||||||||||||||||||
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Medetomidine hydrochloride | 99.94% | Medetomidine hydrochloride is an orally active α2-adrenoceptor agonist (Ki: 1.08 nM). Medetomidine hydrochloride has sedative and analgesic effects. Medetomidine hydrochloride can cause peripheral vasoconstriction through the activation of α2 adrenoceptors on blood vessels. | ||||||||||||||||||||
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References
- [1]. Russak EM, et al. Impact of Deuterium Substitution on the Pharmacokinetics of Pharmaceuticals. Ann Pharmacother. 2019;53(2):211-216. [Content Brief]
- [2]. Davies, M.F., et al., Activation of alpha2 adrenergic receptors suppresses fear conditioning: expression of c-Fos and phosphorylated CREB in mouse amygdala. Neuropsychopharmacology, 2004. 29(2): p. 229-39. [Content Brief]
