1251752-12-1
1251752-12-1
Chemical Structure
Bayer-18
- CAS No.: 1251752-12-1
- Formula:C19H27FN6O2
- Molecular Weight:390.46
IUPAC Name: 1-(tert-butyl)-3-(3-((5-fluoro-4-((1-hydroxy-2-methylpropan-2-yl)amino)pyrimidin-2-yl)amino)phenyl)urea
InChIKey: DYNMZYFOSRSMAC-UHFFFAOYSA-N
SMILES: O=C(NC(C)(C)C)NC1=CC=CC(NC2=NC=C(C(NC(C)(CO)C)=N2)F)=C1
Biological Activity: Bayer-18 is an inhibitor for TYK2. Bayer-18 inhibits the viability of ALCL cell K299, SR786, Mac1 and Mac2a with IC50 of 2-3 µM, and induces apoptosis in K299 and SR786[1].
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Bayer-18 | Bayer-18 is an inhibitor for TYK2. Bayer-18 inhibits the viability of ALCL cell K299, SR786, Mac1 and Mac2a with IC50 of 2-3 µM, and induces apoptosis in K299 and SR786. | |||||||||||||||||||||
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Keywords
