1253584-78-9
Chemical Structure
Hsp90-IN-17
- CAS No.: 1253584-78-9
- Formula:C21H20N4O7
- Molecular Weight:440.41
IUPAC Name: 5-(2,4-dihydroxy-6-(4-nitrophenoxy)phenyl)-N-(piperidin-4-yl)isoxazole-3-carboxamide hydrochloride
InChIKey: WPCKTHWXJWRNOP-UHFFFAOYSA-N
SMILES: O=C(C1=NOC(C2=C(OC3=CC=C([N+]([O-])=O)C=C3)C=C(O)C=C2O)=C1)NC4CCNCC4
Biological Activity: Hsp90-IN-17 is a Hsp90 inhibitor. Hsp90-IN-17 binds to the N-terminal ATP-binding pocket of Hsp90, inhibits its chaperone function, and induces the degradation of Hsp90 client proteins. Hsp90-IN-17 inhibits cancer cell proliferation. Hsp90-IN-17 can be used in the research of ovarian cancer[1][2].
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Hsp90-IN-17 | Hsp90-IN-17 is a Hsp90 inhibitor. Hsp90-IN-17 binds to the N-terminal ATP-binding pocket of Hsp90, inhibits its chaperone function, and induces the degradation of Hsp90 client proteins. Hsp90-IN-17 inhibits cancer cell proliferation. Hsp90-IN-17 can be used in the research of ovarian cancer. | |||||||||||||||||||||
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Keywords
