1257542-38-3
1257542-38-3
Chemical Structure
CaMdr1p-IN-1
- CAS No.: 1257542-38-3
- Formula:C22H20N2O2
- Molecular Weight:344.41
IUPAC Name: (Z)-3-(phenylamino)-4-((1,3,3-trimethylindolin-2-ylidene)methyl)cyclobut-3-ene-1,2-dione
InChIKey: GHIMFDNERWLZKB-AQTBWJFISA-N
SMILES: O=C1C(C(NC2=CC=CC=C2)=C1/C=C3N(C4=C(C\3(C)C)C=CC=C4)C)=O
Biological Activity: CaMdr1p-IN-1 (Compound A) is an inhibitor for the major facilitator superfamily transporter CaMdr1p. CaMdr1p-IN-1 exhibits chemosensitizing efficacy. CaMdr1p-IN-1 synergizes with Fluconazole (HY-B0101), that inhibits CaMdr1p overexpressing Candida albicans with MIC of 10 μM[1].
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CaMdr1p-IN-1 | CaMdr1p-IN-1 (Compound A) is an inhibitor for the major facilitator superfamily transporter CaMdr1p. CaMdr1p-IN-1 exhibits chemosensitizing efficacy. CaMdr1p-IN-1 synergizes with Fluconazole (HY-B0101), that inhibits CaMdr1p overexpressing Candida albicans with MIC of 10 μM. | |||||||||||||||||||||
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