126053-71-2
Chemical Structure
SKF 106760
- CAS No.: 126053-71-2
- Formula:C23H39N9O8S2
- Molecular Weight:633.74
InChIKey: MWLMZCNGBAIZSG-AYMQEEERSA-N
SMILES: N=C(N)NCCC[C@@H]1N(C([C@H](CSSC(C)([C@H](NC([C@@H](NC(CNC1=O)=O)CC(O)=O)=O)C(N)=O)C)NC(C)=O)=O)C
Biological Activity: SKF 106760 is a potent platelet fibrin receptor (glycoprotein IIb/IIIa) antagonist with significant antiplatelet and antithrombotic activities. SKF 106760 inhibits platelet aggregation in dogs in vitro and prevents thrombus formation in stenotic carotid arteries. SKF 106760 has also shown elimination effects against aspirin-resistant thrombi that develop in the setting of high-grade stenosis[1].
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SKF 106760 | SKF 106760 is a potent platelet fibrin receptor (glycoprotein IIb/IIIa) antagonist with significant antiplatelet and antithrombotic activities. SKF 106760 inhibits platelet aggregation in dogs in vitro and prevents thrombus formation in stenotic carotid arteries. SKF 106760 has also shown elimination effects against aspirin-resistant thrombi that develop in the setting of high-grade stenosis. | |||||||||||||||||||||
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Keywords
