1261266-23-2
Chemical Structure
11β-HSD1-IN-25
- CAS No.: 1261266-23-2
- Formula:C21H12F8O
- Molecular Weight:432.31
InChIKey: WOCGWUAYELXILT-WGDLNXRISA-N
SMILES: O=C1/C(CC/C1=C\C2=C(C(F)(F)F)C=CC=C2F)=C/C3=C(C(F)(F)F)C=CC=C3F
Biological Activity: 11β-HSD1-IN-25 is a selective and orally active 11β-HSD1 inhibitor. 11β-HSD1-IN-25 effectively reduces glucocorticoid levels in vitro and serum, and diminishes lipid accumulation in both vitro and vivo. 11β-HSD1-IN-25 modulates lipid metabolism through dual mechanisms: inhibition of 11β-HSD1 and activation of the AMP-activated protein kinase (AMPK) signaling pathway. 11β-HSD1-IN-25 can be used for obesity and related metabolic disorders research[1].
| Cat. No. | Product Name | Purity | Description | Pricing | |||||||||||||||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
|
|
11β-HSD1-IN-25 | 11β-HSD1-IN-25 is a selective and orally active 11β-HSD1 inhibitor. 11β-HSD1-IN-25 effectively reduces glucocorticoid levels in vitro and serum, and diminishes lipid accumulation in both vitro and vivo. 11β-HSD1-IN-25 modulates lipid metabolism through dual mechanisms: inhibition of 11β-HSD1 and activation of the AMP-activated protein kinase (AMPK) signaling pathway. 11β-HSD1-IN-25 can be used for obesity and related metabolic disorders research. | |||||||||||||||||||||
|
loading...
/
|
|||||||||||||||||||||||
Keywords
