1261392-55-5
1261392-55-5
Chemical Structure
(±)-Asenapine-13C,d3 hydrochloride
- CAS No.: 1261392-55-5
- Formula:C1613CH14D3Cl2NO
- Molecular Weight:326.24
InChIKey: FNJQDKSEIVVULU-XSYCCUFUSA-N
SMILES: [H][C@]12C3=C(OC4=C([C@@]1(CN(C2)[13C]([2H])([2H])[2H])[H])C=CC=C4)C=CC(Cl)=C3.Cl
Biological Activity: (±)-Asenapine-13C,d3 (hydrochloride) is 13C and deuterium labeled (±)-Asenapine (hydrochloride)[1].
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(±)-Asenapine-13C,d3 hydrochloride | (±)-Asenapine-13C,d3 (hydrochloride) is 13C and deuterium labeled (±)-Asenapine (hydrochloride). | |||||||||||||||||||||
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Asenapine-13C,d3 hydrochloride | Asenapine-13C,d3 (hydrochloride) is the 13C- and deuterium labeled Asenapine (hydrochloride). Asenapine hydrochloride, an antipsychotic, is a 5-HT (1A, 1B, 2A, 2B, 2C, 5A, 6, 7) and Dopamine (D2, D3, D4) receptor antagonist with Ki values of 0.03-4.0 nM for 5-HT and 1.3, 0.42, 1.1 nM for Dopamine receptor, respectively. | |||||||||||||||||||||
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Asenapine hydrochloride | 99.95% | Asenapine (Org 5222) hydrochloride, an atypical antipsychotic, is an antagonist of serotonin receptors (pKi: 8.4-10.5), adrenoceptors (pKi: 8.9-9.5), dopamine receptors (pKi: 8.9-9.4) and histamine receptors (pKi: 8.2-9.0). Asenapine hydrochloride can be used in the research of schizophrenia and bipolar disorderr. | ||||||||||||||||||||
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References
