127254-10-8
127254-10-8
Chemical Structure
(1R,2S,7R)-Sitafloxacin
Synonym(s): (1R,2S,7R)-DU-6859a; DU-6857
- CAS No.: 127254-10-8
- Formula:C19H18ClF2N3O3
- Molecular Weight:409.81
IUPAC Name: 7-((R)-7-amino-5-azaspiro[2.4]heptan-5-yl)-8-chloro-6-fluoro-1-((1R,2S)-2-fluorocyclopropyl)-4-oxo-1,4-dihydroquinoline-3-carboxylic acid
InChIKey: PNUZDKCDAWUEGK-UHTWSYAYSA-N
SMILES: O=C(C1=CN([C@H]2[C@@H](F)C2)C3=C(C=C(F)C(N(C[C@@H]4N)CC54CC5)=C3Cl)C1=O)O
Biological Activity:
(R)-Sitafloxacin (DU-6857), a stereoisomer of Sitafloxacin (DU-6859a), is also an inhibitor of topoisomerases, with an IC50 of 0.18 μg/mL of DNA gyrase[1].
| Cat. No. | Product Name | Purity | Description | Pricing | |||||||||||||||||||
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(1R,2S,7R)-Sitafloxacin | (R)-Sitafloxacin (DU-6857), a stereoisomer of Sitafloxacin (DU-6859a), is also an inhibitor of topoisomerases, with an IC50 of 0.18 μg/mL of DNA gyrase. |
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(1R,2S,7R)-Sitafloxacin-d4 hydrochloride | (1R,2S,7R)-Sitafloxacin-d4 hydrochloride is deuterium labeled (1R,2S,7R)-Sitafloxacin hydrochloride (HY-B0395D). (R)-Sitafloxacin (DU-6857), a stereoisomer of Sitafloxacin (DU-6859a), is also an inhibitor of topoisomerases, with an IC50 of 0.18 μg/mL of DNA gyrase. |
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References
