1276123-71-7
1276123-71-7
Chemical Structure
Endomorphin 1 acetate
- CAS No.: 1276123-71-7
- Formula:C36H42N6O7
- Molecular Weight:670.75
InChIKey: ISCQEYDGKZTCMS-YAOJAVRNSA-N
SMILES: O=C(N)[C@H](CC1=CC=CC=C1)NC([C@H](CC2=CNC3=CC=CC=C23)NC([C@H]4N(C([C@H](CC5=CC=C(C=C5)O)N)=O)CCC4)=O)=O.CC(O)=O
Biological Activity: Endomorphin 1 acetate, a high affinity, highly selective agonist of the μ-opioid receptor (Ki: 1.11 nM), displays reasonable affinities for kappa3 binding sites, with Ki value between 20 and 30 nM. Endomorphin 1 acetate has antinociceptive properties[1][2][4].
| Cat. No. | Product Name | Purity | Description | Pricing | |||||||||||||||||||
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Endomorphin 1 acetate | 99.92% | Endomorphin 1 acetate, a high affinity, highly selective agonist of the μ-opioid receptor (Ki: 1.11 nM), displays reasonable affinities for kappa3 binding sites, with Ki value between 20 and 30 nM. Endomorphin 1 acetate has antinociceptive properties. | ||||||||||||||||||||
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References
- [1]. Goldberg IE, et al. Pharmacological characterization of endomorphin-1 and endomorphin-2 in mouse brain. J Pharmacol Exp Ther. 1998 Aug;286(2):1007-13. [Content Brief]
- [2]. Tseng LF. The antinociceptive properties of endomorphin-1 and endomorphin-2 in the mouse. Jpn J Pharmacol. 2002 Jul;89(3):216-20. [Content Brief]
- [4]. Koda Y, et al. Synthesis and in vitro evaluation of a library of modified endomorphin 1 peptides. Bioorg Med Chem. 2008 Jun 1;16(11):6286-96. [Content Brief]
Keywords
