127819-95-8
Chemical Structure
L-366811
- CAS. Nr.: 127819-95-8
- Formula:C43H56N8O6
- Molecular Weight:780.95
IUPAC Name: (6aR,13S,16R,18aS,24R,26aS)-16-((1H-indol-3-yl)methyl)-24-benzyl-13-((S)-sec-butyl)-25-methyloctadecahydro-2H,12H-pyrazino[1,2-d]pyrido[1,2-a]pyrrolo[1,2-j][1,4,7,10,13,16]hexaazacyclooctadecine-6,12,15,18,23,26(6aH)-hexaone
InChIKey: XPKURONBKQLLCO-NNEDNOOKSA-N
SMILES: O=C([C@@]1([H])N(CCC1)C([C@H](N(C([C@@]2([H])N(CCNC2)C([C@]3([H])N(CCCC3)C([C@](NC4=O)([H])[C@@H](C)CC)=O)=O)=O)C)CC5=CC=CC=C5)=O)N[C@@H]4CC6=CNC7=CC=CC=C67
Biological Activity: L-366811 is a compound with bradykinin agonist activity, with activity to stimulate phosphatidylinositol turnover and induce uterine contraction. L-366811 stimulates phosphatidylinositol turnover in rat uterine slices and induces rat uterine contraction in vitro, with moderate affinity for the [3H]BK binding site.
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L-366811 | L-366811 is a compound with bradykinin agonist activity, with activity to stimulate phosphatidylinositol turnover and induce uterine contraction. L-366811 stimulates phosphatidylinositol turnover in rat uterine slices and induces rat uterine contraction in vitro, with moderate affinity for the [3H]BK binding site. | |||||||||||||||||||||
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Keywords