129015-60-7
Chemical Structure
3’-Deoxy-5’-O-(4,4’-dimethoxytrityl)-3’-fluorouridine
- CAS No.: 129015-60-7
- Formula:C30H29FN2O7
- Molecular Weight:548.56
IUPAC Name: 1-((2R,3S,4S,5R)-5-((bis(4-methoxyphenyl)(phenyl)methoxy)methyl)-4-fluoro-3-hydroxytetrahydrofuran-2-yl)pyrimidine-2,4(1H,3H)-dione
InChIKey: BUGAQEQILSWXLD-YULOIDQLSA-N
SMILES: O[C@@H]1[C@H](F)[C@@H](COC(C2=CC=CC=C2)(C3=CC=C(OC)C=C3)C4=CC=C(OC)C=C4)O[C@H]1N5C(NC(C=C5)=O)=O
Biological Activity: 3’-Deoxy-5’-O-(4,4’-dimethoxytrityl)-3’-fluorouridine is a purine nucleoside analog. Purine nucleoside analogs have broad antitumor activity targeting indolent lymphoid malignancies. Anticancer mechanisms in this process rely on inhibition of DNA synthesis, induction of apoptosis, etc[1].
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3’-Deoxy-5’-O-(4,4’-dimethoxytrityl)-3’-fluorouridine | 3’-Deoxy-5’-O-(4,4’-dimethoxytrityl)-3’-fluorouridine is a purine nucleoside analog. Purine nucleoside analogs have broad antitumor activity targeting indolent lymphoid malignancies. Anticancer mechanisms in this process rely on inhibition of DNA synthesis, induction of apoptosis, etc. | |||||||||||||||||||||
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