1297262-16-8
1297262-16-8
Chemical Structure
CTK7A
- CAS No.: 1297262-16-8
- Formula:C28H23N2NaO6
- Molecular Weight:506.48
IUPAC Name: sodium 4-(3,5-bis((E)-4-hydroxy-3-methoxystyryl)-1H-pyrazol-1-yl)benzoate
InChIKey: QUZNCOYXNSCQPY-RUACYTINSA-M
SMILES: COC(C=C1/C=C/C2=CC(/C=C/C3=CC(OC)=C(C=C3)O)=NN2C4=CC=C(C=C4)C(O[Na])=O)=C(C=C1)O
Biological Activity: CTK7A is a curcumin derivative with anticancer activity by inhibiting the HAT activity of p300 and reducing the autoacetylation of p300, thereby affecting its interaction with HIF-1α. The inhibition of CTK7A leads to decreased HIF-1α accumulation and activity, which can be used for cancer research[1].
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CTK7A | CTK7A is a curcumin derivative with anticancer activity by inhibiting the HAT activity of p300 and reducing the autoacetylation of p300, thereby affecting its interaction with HIF-1α. The inhibition of CTK7A leads to decreased HIF-1α accumulation and activity, which can be used for cancer research. | |||||||||||||||||||||
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