1312815-93-2

PF-4693627 Chemical Structure
1312815-93-2

Chemical Structure

PF-4693627

  • CAS No.: 1312815-93-2
  • Formula:C26H29Cl2N3O3
  • Molecular Weight:502.43

IUPAC Name: 1-(5-chloro-6-(4-chlorophenyl)benzo[d]oxazol-2-yl)-N-((1S,3S)-3-(hydroxymethyl)cyclohexyl)piperidine-4-carboxamide

InChIKey: CPDNPVKDQXLYHO-JXFKEZNVSA-N

SMILES: O=C(C1CCN(C2=NC3=CC(Cl)=C(C4=CC=C(Cl)C=C4)C=C3O2)CC1)N[C@@H]5C[C@@H](CO)CCC5

Biological Activity: PF-4693627 is a potent, selective and orally bioavailable microsomal prostaglandin E synthase-1 (mPGES-1) inhibitor (IC50=3 nM) for the treatment of inflammation caused by osteoarthritis (OA) and rheumatoid arthritis (RA)[1].

Cat. No. Product Name Purity Description Pricing
HY-125415
PF-4693627 99.63% PF-4693627 is a potent, selective and orally bioavailable microsomal prostaglandin E synthase-1 (mPGES-1) inhibitor (IC50=3 nM) for the treatment of inflammation caused by osteoarthritis (OA) and rheumatoid arthritis (RA).
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