1330061-67-0
Chemical Structure
CAIX Inhibitor S4
- CAS No.: 1330061-67-0
- Formula:C15H17N3O4S
- Molecular Weight:335.38
IUPAC Name: 4-(3-(3,5-dimethylphenyl)ureido)phenyl sulfamate
InChIKey: HGVHSNXRZYOTPD-UHFFFAOYSA-N
SMILES: O=C(NC1=CC(C)=CC(C)=C1)NC2=CC=C(C=C2)OS(=O)(N)=O
Biological Activity: CAIX Inhibitor S4 is a potent and selective inhibitor of carbonic anhydrase IX/XII (CA IX/XII), with a Ki of 7 nM and 2 nM, respectively. CAIX Inhibitor S4 also inhibits CA II and CA I (Ki=546 and 5600 nM, respectively). CAIX Inhibitor S4 can inhibit the number of lung metastasis in orthotopic MDA-MB-231 mouse model without affecting primary tumor growth[1].
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CAIX Inhibitor S4 | 99.04% | CAIX Inhibitor S4 is a potent and selective inhibitor of carbonic anhydrase IX/XII (CA IX/XII), with a Ki of 7 nM and 2 nM, respectively. CAIX Inhibitor S4 also inhibits CA II and CA I (Ki=546 and 5600 nM, respectively). CAIX Inhibitor S4 can inhibit the number of lung metastasis in orthotopic MDA-MB-231 mouse model without affecting primary tumor growth. | ||||||||||||||||||||
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Keywords
