1334314-19-0
Chemical Structure
MK-8325 dihydrochloride
- CAS No.: 1334314-19-0
- Formula:C43H54Cl2F2N8O6Si
- Molecular Weight:915.93
IUPAC Name: methyl ((S)-1-((S)-4,4-difluoro-2-(5-(4-(2-((R)-1-((methoxycarbonyl)-L-valyl)-3,3-dimethyl-1,3-azasilolidin-5-yl)-1H-naphtho[1,2-d]imidazol-7-yl)phenyl)-1H-imidazol-2-yl)pyrrolidin-1-yl)-3-methyl-1-oxobutan-2-yl)carbamate dihydrochloride
InChIKey: IUEFJCXFZOOGJY-RYYFUXLTSA-N
SMILES: O=C([C@H](C(C)C)NC(OC)=O)N1C[Si](C[C@H]1C2=NC3=CC=C4C(C=CC(C5=CC=C(C6=CN=C([C@@H]7CC(CN7C([C@H](C(C)C)NC(OC)=O)=O)(F)F)N6)C=C5)=C4)=C3N2)(C)C.Cl.Cl
Biological Activity: MK-8325 (dihydrochloride) is an inhibitor of HCV NS5A with oral activity. MK-8325 exhibits minimal inhibition on hERG at the concentration of 30 mM[1].
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MK-8325 dihydrochloride | MK-8325 (dihydrochloride) is an inhibitor of HCV NS5A with oral activity. MK-8325 exhibits minimal inhibition on hERG at the concentration of 30 mM. | |||||||||||||||||||||
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Keywords
