134439-56-8
Chemical Structure
LiLo
- CAS No.: 134439-56-8
- Formula:C39H57N9O18S
- Molecular Weight:971.98
IUPAC Name: 3,6,9,19,22,25-hexakis(carboxymethyl)-14-(4-isothiocyanatobenzyl)-11,17-dioxo-3,6,9,12,16,19,22,25-octaazaheptacosanedioic acid
InChIKey: OWFPZFPOOSUIIA-UHFFFAOYSA-N
SMILES: O=C(CN(CCN(CCN(CC(NCC(CC1=CC=C(C=C1)N=C=S)CNC(CN(CCN(CCN(CC(O)=O)CC(O)=O)CC(O)=O)CC(O)=O)=O)=O)CC(O)=O)CC(O)=O)CC(O)=O)O
Biological Activity: LiLo is a new bifunctional chelator that has the activity of forming kinetically stable chelates with metal ions (such as indium). After using LiLo to bind indium-111 to monoclonal antibodies, the in vitro stability and in vivo biodistribution of the conjugates are superior to those using other chelators.
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LiLo | LiLo is a new bifunctional chelator that has the activity of forming kinetically stable chelates with metal ions (such as indium). After using LiLo to bind indium-111 to monoclonal antibodies, the in vitro stability and in vivo biodistribution of the conjugates are superior to those using other chelators. | |||||||||||||||||||||
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Keywords
