134523-09-4
134523-09-4
Chemical Structure
(Rac)-3-OH-Simvastatin
- CAS No.: 134523-09-4
- Formula:C25H38O6
- Molecular Weight:434.57
InChIKey: WJKSTNFUSXHVRJ-UHFFFAOYSA-N
SMILES: O=C1OC(CC(C1)O)CCC2C(C)C=CC3=CC(C)(CC(C32)OC(C(C)(CC)C)=O)O
Biological Activity: (Rac)-3-OH-Simvastatin is a metabolite of Simvastatin (HY-17502). Simvastatin is an orally active competitive inhibitor of HMG-CoA reductase (HMGCR) with a Ki of 0.2 nM[1].
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(Rac)-3-OH-Simvastatin | (Rac)-3-OH-Simvastatin is a metabolite of Simvastatin (HY-17502). Simvastatin is an orally active competitive inhibitor of HMG-CoA reductase (HMGCR) with a Ki of 0.2 nM. | |||||||||||||||||||||
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References
Keywords
