1345866-66-1

4-(6-Methyl-1,2,4,5-tetrazin-3-yl)benzoic acid Chemical Structure
1345866-66-1

Chemical Structure

4-(6-Methyl-1,2,4,5-tetrazin-3-yl)benzoic acid

  • CAS. Nr.: 1345866-66-1
  • Formula:C10H8N4O2
  • Molecular Weight:216.20

IUPAC Name: 4-(6-methyl-1,2,4,5-tetrazin-3-yl)benzoic acid

InChIKey: VIRCHPVFFZGAJH-UHFFFAOYSA-N

SMILES: O=C(O)C=1C=CC(=CC1)C2=NN=C(N=N2)C

Biological Activity: 4-(6-Methyl-1,2,4,5-tetrazin-3-yl) benzoic acid is an asymmetric tetrazine derivative and a bioorthogonal reaction partner. 4-(6-Methyl-1,2,4,5-tetrazin-3-yl) benzoic acid can be conjugated with Bevacizumab (HY-P9906) via EDC/NHS activation while retaining the VEGF-binding affinity of the antibody, thus constructing a targeting agent for pretargeted immuno-PET/NIRF imaging[1][2].

Art. -Nr. Produktname Reinheit Beschreibung Pricing
HY-W422109 		4-(6-Methyl-1,2,4,5-tetrazin-3-yl)benzoic acid 4-(6-Methyl-1,2,4,5-tetrazin-3-yl) benzoic acid is an asymmetric tetrazine derivative and a bioorthogonal reaction partner. 4-(6-Methyl-1,2,4,5-tetrazin-3-yl) benzoic acid can be conjugated with Bevacizumab (HY-P9906) via EDC/NHS activation while retaining the VEGF-binding affinity of the antibody, thus constructing a targeting agent for pretargeted immuno-PET/NIRF imaging.
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This product is a controlled substance and not for sale in your territory.

This product is not for sale in your territory.

This compound is listed in the SVHC (Substances of Very High Concern) candidate list of ECHA (European Chemicals Agency).

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References

Keywords