1345866-66-1

4-(6-Methyl-1,2,4,5-tetrazin-3-yl)benzoic acid Chemical Structure
1345866-66-1

Chemical Structure

4-(6-Methyl-1,2,4,5-tetrazin-3-yl)benzoic acid

  • CAS No.: 1345866-66-1
  • Formula:C10H8N4O2
  • Molecular Weight:216.20

IUPAC Name: 4-(6-methyl-1,2,4,5-tetrazin-3-yl)benzoic acid

InChIKey: VIRCHPVFFZGAJH-UHFFFAOYSA-N

SMILES: O=C(O)C=1C=CC(=CC1)C2=NN=C(N=N2)C

Biological Activity: 4-(6-Methyl-1,2,4,5-tetrazin-3-yl) benzoic acid is an asymmetric tetrazine derivative and a bioorthogonal reaction partner. 4-(6-Methyl-1,2,4,5-tetrazin-3-yl) benzoic acid can be conjugated with Bevacizumab (HY-P9906) via EDC/NHS activation while retaining the VEGF-binding affinity of the antibody, thus constructing a targeting agent for pretargeted immuno-PET/NIRF imaging[1][2].

Cat. No. Product Name Purity Description Pricing
HY-W422109 		4-(6-Methyl-1,2,4,5-tetrazin-3-yl)benzoic acid 4-(6-Methyl-1,2,4,5-tetrazin-3-yl) benzoic acid is an asymmetric tetrazine derivative and a bioorthogonal reaction partner. 4-(6-Methyl-1,2,4,5-tetrazin-3-yl) benzoic acid can be conjugated with Bevacizumab (HY-P9906) via EDC/NHS activation while retaining the VEGF-binding affinity of the antibody, thus constructing a targeting agent for pretargeted immuno-PET/NIRF imaging.
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