1348755-27-0
1348755-27-0
Chemical Structure
NBUMP
- CAS No.: 1348755-27-0
- Formula:C26H39N3O2
- Molecular Weight:425.62
IUPAC Name: N-(4-(4-(2-methoxyphenyl)piperazin-1-yl)butyl)adamantane-2-carboxamide
InChIKey: PFZGQOGDOAZQFC-UHFFFAOYSA-N
SMILES: O=C(NCCCCN1CCN(C=2C=CC=CC2OC)CC1)C3C4CC5CC(C4)CC3C5
Biological Activity: NBUMP is a 5-HT1A receptor ligand with a 5-HT1A receptor Ki of 0.1 nM, α1-adrenergic receptor Ki of 46 nM, and a 5-HT1A receptor-to-α1-adrenergic receptor selectivity ratio of 460.NBUMP binds to the 5-HT1A receptor with high affinity.NBUMP binds to the α1-adrenergic receptor with lower affinity[1].
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NBUMP | NBUMP is a 5-HT1A receptor ligand with a 5-HT1A receptor Ki of 0.1 nM, α1-adrenergic receptor Ki of 46 nM, and a 5-HT1A receptor-to-α1-adrenergic receptor selectivity ratio of 460.NBUMP binds to the 5-HT1A receptor with high affinity.NBUMP binds to the α1-adrenergic receptor with lower affinity. | |||||||||||||||||||||
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References
Keywords
