1354825-62-9
1354825-62-9
Chemical Structure
WEHI-345 analog
- CAS No.: 1354825-62-9
- Formula:C23H25N7O
- Molecular Weight:415.49
IUPAC Name: N-(2-(4-amino-3-(p-tolyl)-1H-pyrazolo[3,4-d]pyrimidin-1-yl)-2-methylpropyl)-3-methylpicolinamide
InChIKey: ZCZGSEXBXXYQQC-UHFFFAOYSA-N
SMILES: O=C(C1=NC=CC=C1C)NCC(C)(N2N=C(C3=CC=C(C)C=C3)C4=C(N)N=CN=C42)C
Biological Activity: WEHI-345 analog is the analog of WEHI-345. WEHI-345 is a potent and selective RIPK2 kinase inhibitor with an IC50 of 0.13 μM, which delays RIPK2 ubiquitylation and NF-κB activation on oligomerization domain (NOD) stimulation[1].
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WEHI-345 analog | 98.41% | WEHI-345 analog is the analog of WEHI-345. WEHI-345 is a potent and selective RIPK2 kinase inhibitor with an IC50 of 0.13 μM, which delays RIPK2 ubiquitylation and NF-κB activation on oligomerization domain (NOD) stimulation. | ||||||||||||||||||||
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References
Keywords
