1362-42-1
Chemical Structure
Absinthin
- CAS. Nr.: 1362-42-1
- Formula:C30H40O6
- Molecular Weight:496.64
InChIKey: PZHWYURJZAPXAN-ILOFNVQHSA-N
SMILES: CC1=C[C@@]2([H])[C@]3([H])[C@]1([C@](OC4=O)([H])[C@@]([C@@H]4C)([H])CC[C@@]3(O)C)[C@]5([H])[C@@]2([H])[C@]([C@]6(O)C)([H])C([C@](OC7=O)([H])[C@@]([C@@H]7C)([H])CC6)=C5C
Biological Activity: Absinthin is a structurally unique triterpene, and is responsible for the high bitter value of wormwood. Absinthin is an agonist of the bitter taste receptor hTAS2R46, which reduces cytosolic Ca2+-rises induced by histamine by a receptor-specific mechanism mediated by hTAS2R46[1][2][3].
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Absinthin | 98.0% | Absinthin is a structurally unique triterpene, and is responsible for the high bitter value of wormwood. Absinthin is an agonist of the bitter taste receptor hTAS2R46, which reduces cytosolic Ca2+-rises induced by histamine by a receptor-specific mechanism mediated by hTAS2R46. | ||||||||||||||||||||
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Absinthin (Standard) | ≥98% | Absinthin (Standard) is the analytical standard of Absinthin. This product is intended for research and analytical applications. Absinthin is a structurally unique triterpene, and is responsible for the high bitter value of wormwood. Absinthin is an agonist of the bitter taste receptor hTAS2R46, which reduces cytosolic Ca2+-rises induced by histamine by a receptor-specific mechanism mediated by hTAS2R46. | ||||||||||||||||||||
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- [1]. Zhang W, et al. Total synthesis of absinthin. J Am Chem Soc. 2005 Jan 12;127(1):18-9. [Content Brief]
- [2]. Lachenmeier DW, et al. Absinthe--a review. Crit Rev Food Sci Nutr. 2006;46(5):365-77. [Content Brief]
- [3]. Talmon M, et al. Absinthin, an agonist of the bitter taste receptor hTAS2R46, uncovers an ER-to-mitochondria Ca2+-shuttling event. J Biol Chem. 2019 Aug 16;294(33):12472-12482. [Content Brief]
Keywords
