1372127-19-9
Chemical Structure
ALK4290 dihydrochloride
Synonym(s): AKST4290 dihydrochloride; BI144807 dihydrochloride
- CAS No.: 1372127-19-9
- Formula:C27H36Cl3N5O3
- Molecular Weight:584.97
InChIKey: IUDHVSKPEAGQGJ-MQWQBNKOSA-N
SMILES: O=C(C1=CC(NC([C@@H](CC2)N(C3CCN(CC4=CC=C(Cl)C(C)=C4)CC3)C2=O)=O)=NC(C)=C1)N(C)C.[H]Cl.[H]Cl
Biological Activity: ALK4290 dihydrochloride (AKST4290 dihydrochlorid) is a potent and orally active CCR3 inhibitor extracted from patent US20130261153A1, compound Example 2, with a Ki of 3.2 nM for hCCR3[1]. ALK4290 can be used for the research of neovascular age-related macular degeneration and Parkinsonism[2][3].
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ALK4290 dihydrochloride | ALK4290 dihydrochloride (AKST4290 dihydrochlorid) is a potent and orally active CCR3 inhibitor extracted from patent US20130261153A1, compound Example 2, with a Ki of 3.2 nM for hCCR3. ALK4290 can be used for the research of neovascular age-related macular degeneration and Parkinsonism. | |||||||||||||||||||||
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Keywords
