1380342-00-6
1380342-00-6
Chemical Structure
GAL-021 sulfate
- CAS No.: 1380342-00-6
- Formula:C11H24N6O5S
- Molecular Weight:352.41
IUPAC Name: 6-(methoxy(methyl)amino)-N2,N4-dipropyl-1,3,5-triazine-2,4-diamine sulfate
InChIKey: FMJQTHGXXTYHSQ-UHFFFAOYSA-N
SMILES: O=S(O)(O)=O.CCCNC1=NC(NCCC)=NC(N(C)OC)=N1
Biological Activity: GAL-021 sulfate is a potent BKCa-channel blocker. GAL-021 sulfate inhibits KCa1.1 in GH3 cells. GAL-021 sulfate is a novel breathing control modulator that is based on selective modification of the almitrine pharmacophore. GAL-021 sulfate increases minute ventilation in rats and non-human primates[1][2].
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GAL-021 sulfate | GAL-021 sulfate is a potent BKCa-channel blocker. GAL-021 sulfate inhibits KCa1.1 in GH3 cells. GAL-021 sulfate is a novel breathing control modulator that is based on selective modification of the almitrine pharmacophore. GAL-021 sulfate increases minute ventilation in rats and non-human primates. | |||||||||||||||||||||
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References
- [1]. Golder FJ, et al. Identification and Characterization of GAL-021 as a Novel Breathing Control Modulator. Anesthesiology. 2015 Nov;123(5):1093-104. [Content Brief]
- [2]. J F McLeod, et al. GAL-021, a new intravenous BKCa-channel blocker, is well tolerated and stimulates ventilation in healthy volunteers. Br J Anaesth. 2014 Nov;113(5):875-83. [Content Brief]
Keywords
