139403-31-9
Chemical Structure
Pimilprost
Synonym(s): SM 10902
- CAS No.: 139403-31-9
- Formula:C23H40O5
- Molecular Weight:396.56
IUPAC Name: methyl 2-(2-((2R,3aS,4R,5R,6aS)-5-hydroxy-4-((3S,5S,E)-3-hydroxy-5-methylnon-1-en-1-yl)octahydropentalen-2-yl)ethoxy)acetate
InChIKey: SLDLSMFNGFIPNI-RXYUHBJGSA-N
SMILES: CCCC[C@H](C)C[C@H](O)/C=C/[C@@H]1[C@]2([H])[C@](C[C@@H](CCOCC(OC)=O)C2)([H])C[C@H]1O
Biological Activity: Pimilprost (SM 10902) is a prostaglandin I1 analogue. Pimilprost exhibits antithrombotic and increases cAMP levels. Pimilprost can promote wound healing through the stimulation of angiogenesis and the improvement of blood flow in diabetic mice. Pimilprost can be used for the research of metabolic and cardiovascular disease, such as diabetes[1][2].
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Pimilprost | Pimilprost (SM 10902) is a prostaglandin I1 analogue. Pimilprost exhibits antithrombotic and increases cAMP levels. Pimilprost can promote wound healing through the stimulation of angiogenesis and the improvement of blood flow in diabetic mice. Pimilprost can be used for the research of metabolic and cardiovascular disease, such as diabetes. | |||||||||||||||||||||
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- [1]. Nishimura T, et al. Antithrombotic effect of topically applied 3-oxa-methano-prostaglandin I1 in the microcirculation and antiplatelet functions of its active form. Prostaglandins. 1996 Feb;51(2):149-59. [Content Brief]
- [2]. Yamamoto T, et al. Effect of topical application of a stable prostacyclin analogue, SM-10902 on wound healing in diabetic mice. Eur J Pharmacol. 1996 Apr 29;302(1-3):53-60. [Content Brief]
Keywords
