1399103-28-6
Chemical Structure
RO5487624
- CAS No.: 1399103-28-6
- Formula:C16H25ClN2O3S
- Molecular Weight:360.90
IUPAC Name: 2-chloro-5-((((1R,5S)-5-hydroxy-1,3,3-trimethylcyclohexyl)methyl)amino)benzenesulfonamide
InChIKey: YSFDGLZSRNZXRG-LRDDRELGSA-N
SMILES: O=S(C1=CC(NC[C@]2(C)CC(C)(C)C[C@H](O)C2)=CC=C1Cl)(N)=O
Biological Activity: RO5487624, an analogue of RO5464466 (HY-120690), is an orally active hemagglutinin (HA) inhibitor of influenza H1N1 viruses that abolishes influenza virus fusion by blocking HA conformational changes in low pH environments. RO5487624 displays a protective effect on mice that are lethally challenged with influenza H1N1 virus[1].
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RO5487624 | RO5487624, an analogue of RO5464466 (HY-120690), is an orally active hemagglutinin (HA) inhibitor of influenza H1N1 viruses that abolishes influenza virus fusion by blocking HA conformational changes in low pH environments. RO5487624 displays a protective effect on mice that are lethally challenged with influenza H1N1 virus. | |||||||||||||||||||||
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Keywords
