1402438-37-2
1402438-37-2
Chemical Structure
Trk-IN-1
- CAS No.: 1402438-37-2
- Formula:C24H20F3N5O3
- Molecular Weight:483.44
IUPAC Name: (S)-N-(5-(7-(1-hydroxypropan-2-yl)-7H-pyrrolo[2,3-d]pyrimidine-5-carbonyl)pyridin-3-yl)-2-(4-(trifluoromethyl)phenyl)acetamide
InChIKey: FFWLYMMISQUEAL-AWEZNQCLSA-N
SMILES: O=C(C1=CN=CC(NC(CC2=CC=C(C=C2)C(F)(F)F)=O)=C1)C3=CN([C@@H](C)CO)C4=NC=NC=C34
Biological Activity: Trk-IN-1 (example 9), a potent tropomyosin-related kinase (Trk) inhibitor, shows potency against TrkA (3.7 nM) and TrkB (94 nM), respectively[1].
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Trk-IN-1 | Trk-IN-1 (example 9), a potent tropomyosin-related kinase (Trk) inhibitor, shows potency against TrkA (3.7 nM) and TrkB (94 nM), respectively. | |||||||||||||||||||||
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References
Keywords
