1. Neuronal Signaling Protein Tyrosine Kinase/RTK
  2. Trk Receptor
  3. Trk-IN-1

Trk-IN-1 (example 9), a potent tropomyosin-related kinase (Trk) inhibitor, shows potency against TrkA (3.7 nM) and TrkB (94 nM), respectively.

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Trk-IN-1 Chemical Structure

Trk-IN-1 Chemical Structure

CAS No. : 1402438-37-2

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Description

Trk-IN-1 (example 9), a potent tropomyosin-related kinase (Trk) inhibitor, shows potency against TrkA (3.7 nM) and TrkB (94 nM), respectively[1].

Molecular Weight

483.44

Formula

C24H20F3N5O3

CAS No.
SMILES

O=C(C1=CN=CC(NC(CC2=CC=C(C=C2)C(F)(F)F)=O)=C1)C3=CN([C@@H](C)CO)C4=NC=NC=C34

Shipping

Room temperature in continental US; may vary elsewhere.

Storage

Please store the product under the recommended conditions in the Certificate of Analysis.

Purity & Documentation
References
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Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

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Trk-IN-1
Cat. No.:
HY-12327
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