1403458-28-5
1403458-28-5
Chemical Structure
PI3K-IN-2
- CAS No.: 1403458-28-5
- Formula:C28H29F2N3O5
- Molecular Weight:525.54
IUPAC Name: (R)-8-(1-(3,5-difluorophenyl)pyrrolidin-2-yl)-6-(morpholine-4-carbonyl)-2-morpholino-4H-chromen-4-one
InChIKey: CPFXYHKMOTWOFK-XMMPIXPASA-N
SMILES: O=C1C=C(N2CCOCC2)OC3=C([C@@H]4N(C5=CC(F)=CC(F)=C5)CCC4)C=C(C(N6CCOCC6)=O)C=C13
Biological Activity: PI3K-IN-2 (compound 10) is a potent and orally active PI3Kβ/δ (IC50=7.1/8.6 nM) inhibitor with excellent selectivity versus PI3Kσ and PI3Kγ (IC50=13/190 nM, respectively)[1].
| Cat. No. | Product Name | Purity | Description | Pricing | |||||||||||||||||||
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PI3K-IN-2 | 99.62% | PI3K-IN-2 (compound 10) is a potent and orally active PI3Kβ/δ (IC50=7.1/8.6 nM) inhibitor with excellent selectivity versus PI3Kσ and PI3Kγ (IC50=13/190 nM, respectively). | ||||||||||||||||||||
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References
Keywords
