1414873-26-9
Chemical Structure
Anticancer agent 299
- CAS No.: 1414873-26-9
- Formula:C25H20F3N3O
- Molecular Weight:435.44
InChIKey: QDNDEIIJJNPBHP-UHFFFAOYSA-N
SMILES: FC(F)(C1=CC=C(C=C1)C2=CC(C3=CC=CC4=C3C=CC=C4)=NC(N5CCOCC5)=N2)F
Biological Activity: Anticancer agent 299 (compound P12) is a cell-cycle inhibitor, senescence inducer, apoptosis inducer, and antiproliferative agent. Anticancer agent 299 exhibits selective activity against cancer cells with minimal effects on non-tumoral chondrocyte cells at relevant concentrations. Anticancer agent 299 can be used for the research of ER+/HER2− breast cancer and BRAF-mutant melanoma[1].
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Anticancer agent 299 | Anticancer agent 299 (compound P12) is a cell-cycle inhibitor, senescence inducer, apoptosis inducer, and antiproliferative agent. Anticancer agent 299 exhibits selective activity against cancer cells with minimal effects on non-tumoral chondrocyte cells at relevant concentrations. Anticancer agent 299 can be used for the research of ER+/HER2− breast cancer and BRAF-mutant melanoma. | |||||||||||||||||||||
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Keywords
