1415400-62-2
Chemical Structure
Ractopamine-13C6
- CAS No.: 1415400-62-2
- Formula:C1213C6H23NO3
- Molecular Weight:307.34
IUPAC Name: 4-(1-hydroxy-2-((4-(4-hydroxyphenyl)butan-2-yl)amino)ethyl)phenol-13C6
InChIKey: YJQZYXCXBBCEAQ-NQMMCGFVSA-N
SMILES: O[13C]1=[13C]([H])[13C]([H])=[13C](C(O)CNC(C)CCC2=CC=C(O)C=C2)[13C]([H])=[13C]1[H]
Biological Activity: Ractopamine-13C6 is the 13C-labeled Ractopamine (HY-113781). Ractopamine (LY031537 free base) is a potent and orally active β-adrenergic receptor (βAR) agonist with Kd value of ~25 nM for pig β1AR and β2AR. Ractopamine also is a mTAAR1 agonist with an EC50 of 16 μM. Ractopamine promotes muscle mass development, limits fat deposition, reduces feed consumption, increases total cellular protein synthesis, and improves growth rate and feed efficiency in finishing swine. Ractopamine can be used for researching to increase lean tissue growth and improve production efficiency in pigs[1][2][3][4][5].
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Ractopamine-13C6 | Ractopamine-13C6 is the 13C-labeled Ractopamine (HY-113781). Ractopamine (LY031537 free base) is a potent and orally active β-adrenergic receptor (βAR) agonist with Kd value of ~25 nM for pig β1AR and β2AR. Ractopamine also is a mTAAR1 agonist with an EC50 of 16 μM. Ractopamine promotes muscle mass development, limits fat deposition, reduces feed consumption, increases total cellular protein synthesis, and improves growth rate and feed efficiency in finishing swine. Ractopamine can be used for researching to increase lean tissue growth and improve production efficiency in pigs. | |||||||||||||||||||||
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- [1]. Athayde NB, et al. Stress susceptibility in pigs supplemented with ractopamine. J Anim Sci. 2013;91(9):4180-4187. [Content Brief]
- [2]. Anderson PT, et al. Ractopamine increases total and myofibrillar protein synthesis in cultured rat myotubes. J Nutr. 1990;120(12):1677-1683. [Content Brief]
- [3]. S. E. Mills, Biological basis of the ractopamine response, Journal of Animal Science, Volume 80, Issue E-suppl_2, 2002, Pages E28-E32.
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