142741-24-0
142741-24-0
Chemical Structure
Conophylline
- CAS No.: 142741-24-0
- Formula:C44H50N4O10
- Molecular Weight:794.89
InChIKey: QZRIMAMDGWAHPQ-UHFFFAOYSA-N
SMILES: CC[C@]1(C2)[C@@]3([H])[C@](C4=CC(O)=C5OC)(CCN3[C@@](C(C=C([C@]6(CCN7C[C@]8([H])[C@@]9([H])O8)[C@]7([H])[C@@]9(C%10)CC)C(NC6=C%10C(OC)=O)=C%11)=C%11O%12)([H])[C@@]%12([H])[C@H]1O)C(NC4=C5OC)=C2C(OC)=O
Biological Activity: Conophylline is a vinca alkaloid extracted from leaves of a tropical plant Ervatamia microphylla. Conophylline is a differentiation inducer of for pancreatic cells. Conophylline suppresses HSC and induces apoptosis[1][2].
| Cat. No. | Product Name | Purity | Description | Pricing | |||||||||||||||||||
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Conophylline | 98.04% | Conophylline is a vinca alkaloid extracted from leaves of a tropical plant Ervatamia microphylla. Conophylline is a differentiation inducer of for pancreatic cells. Conophylline suppresses HSC and induces apoptosis. | ||||||||||||||||||||
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References
- [1]. Kojima I, et al. Conophylline: a novel differentiation inducer for pancreatic beta cells. Int J Biochem Cell Biol. 2006;38(5-6):923-30. [Content Brief]
- [2]. Kubo N, et al. Conophylline suppresses hepatic stellate cells and attenuates thioacetamide-induced liver fibrosis in rats. Liver Int. 2014 Aug;34(7):1057-67. [Content Brief]
Keywords
