1428327-31-4
1428327-31-4
Chemical Structure
JNJ-47965567
- CAS No.: 1428327-31-4
- Formula:C28H32N4O2S
- Molecular Weight:488.64
IUPAC Name: N-((4-(4-phenylpiperazin-1-yl)tetrahydro-2H-pyran-4-yl)methyl)-2-(phenylthio)nicotinamide
InChIKey: XREFXUCWSYMIOG-UHFFFAOYSA-N
SMILES: O=C(C1=CC=CN=C1SC2=CC=CC=C2)NCC3(N4CCN(C5=CC=CC=C5)CC4)CCOCC3
Biological Activity: JNJ-47965567 is a centrally permeable, high-affinity, selective P2X7 antagonist, with pKis of 7.9 and 8.7 for human and rat P2X7, respectively. JNJ-47965567 can be used to probe the role of central P2X7 in rodent models of CNS pathophysiology[1].
| Cat. No. | Product Name | Purity | Description | Pricing | |||||||||||||||||||
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JNJ-47965567 | 99.87% | JNJ-47965567 is a centrally permeable, high-affinity, selective P2X7 antagonist, with pKis of 7.9 and 8.7 for human and rat P2X7, respectively. JNJ-47965567 can be used to probe the role of central P2X7 in rodent models of CNS pathophysiology. | ||||||||||||||||||||
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JNJ-47965567 (Standard) | ≥98% | JNJ-47965567 (Standard) is the analytical standard of JNJ-47965567 (HY-101418). This product is intended for research and analytical applications. JNJ-47965567 is a centrally permeable, high-affinity, selective P2X7 antagonist, with pKis of 7.9 and 8.7 for human and rat P2X7, respectively. JNJ-47965567 can be used to probe the role of central P2X7 in rodent models of CNS pathophysiology. | ||||||||||||||||||||
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References
Keywords
