1429218-79-0
Chemical Structure
UAWJ246
- CAS No.: 1429218-79-0
- Formula:C25H34N4O6
- Molecular Weight:486.57
IUPAC Name: benzyl ((S)-1-(((S)-4-(cyclopropylamino)-3,4-dioxo-1-((S)-2-oxopyrrolidin-3-yl)butan-2-yl)amino)-4-methyl-1-oxopentan-2-yl)carbamate
InChIKey: OFRZKNOAEKYJPI-IHPCNDPISA-N
SMILES: [C@@H](C[C@H]1C(=O)NCC1)(NC([C@@H](NC(OCC2=CC=CC=C2)=O)CC(C)C)=O)C(C(NC3CC3)=O)=O
Biological Activity: UAWJ246 is a covalent reversible inhibitor of the SARS-CoV-2 main protease (Mpro), with an IC50 of 0.045 μM and a Ki of 0.036 μM. UAWJ246 exhibits potent antiviral activity by inhibiting SARS-CoV-2 viral replication and shows low cytotoxicity. UAWJ246 can be used in research related to SARS-CoV-2 infection, such as studies on COVID-19[1][2].
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UAWJ246 | UAWJ246 is a covalent reversible inhibitor of the SARS-CoV-2 main protease (Mpro), with an IC50 of 0.045 μM and a Ki of 0.036 μM. UAWJ246 exhibits potent antiviral activity by inhibiting SARS-CoV-2 viral replication and shows low cytotoxicity. UAWJ246 can be used in research related to SARS-CoV-2 infection, such as studies on COVID-19. | |||||||||||||||||||||
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Keywords
